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Renowned British theoretical physicist Stephen Hawkingdied at 76 last nightat his home in Cambridge, England.

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His 1988 bookA Brief History of Timebecame an international best seller.

My love and thoughts are with his extraordinary family.

I will always remember his reaction to his first viewing of The Theory of Everything.

Travel well Steve, to your rightful place among the stars.

I trust that in death you have fulfilled your lifes ambition, to know the mind of God.

Other tributes came from the castofThe Big Bang Theory, includingKaley Cuoco,Johnny Galecki, andMayim Bialik.

In loving memory of Stephen Hawking.

It was an honor to have him on The#BigBangTheory.

Thank you for inspiring us and the world.pic.twitter.com/9rWoYqIToy

John Oliver.

Stephen Hawking was a brilliant man, but he was also an incredibly funny man.

Farewell to Stephen Hawking, the most intelligent guest star in the brief history of The Simpsonspic.twitter.com/po3fIHgEdh

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@TheSimpsonsRIP Stephen Hawking.

A sense of humor as vast as the universe.pic.twitter.com/528kWRhfVR

Star Trek: The Next GenerationsBrent Spiner.

Honored to have spent time with him.

Astrophysicist Neil deGrasse Tyson.

His passing has left an intellectual vacuum in his wake.

But it’s not empty.

Think of it as a kind of vacuum energy permeating the fabric of spacetime that defies measure.

Stephen Hawking, RIP 1942-2018.pic.twitter.com/nAanMySqkt

Canadian astronaut Chris Hadfield.

Genius is so fine and rare.

You inspired and taught us all.pic.twitter.com/9Drdnv2eEe

And more.

Genuinely very sad to hear that.

If you havent, read A Brief History of Time.

Itll make the world feel more amazing and beautiful and strange.

Itll also make you feel smart and stupid all at once.

I am very saddened to hear of Stephen Hawkings passing.

You are shining in the heavens you so loved now!

theres a big black hole in my heart hours before Pi day.

It is a great loss to the scientific community.

He was a hero to so many.